Hepatitis B Cases by Country

Explore comprehensive Hepatitis B statistics by country using 2022 WHO estimates and national reporting data from 169 countries worldwide. The dataset highlights the global distribution of chronic HBV infections and helps researchers, healthcare professionals, and policymakers compare disease burden across regions.

This dataset tracks estimated chronic Hepatitis B (HBV) infections across 169 countries in 2022 using WHO-based reporting and national prevalence estimates. The figures highlight the unequal global distribution of HBV, with the largest burdens concentrated in parts of Asia and sub-Saharan Africa.

Global Hepatitis B Statistics 2022

Chronic Hepatitis B remains one of the world's largest infectious disease burdens, affecting hundreds of millions of people worldwide. While vaccination programs have reduced transmission in many regions, HBV continues to place major pressure on healthcare systems in highly endemic countries.

Key Takeaways

  • China reported the highest estimated Hepatitis B burden in 2022 with 79.7 million chronic infections.
  • India followed with 29.8 million cases, while Indonesia recorded more than 17.5 million cases.
  • Nigeria ranked among the most affected countries in Africa with roughly 14.4 million chronic HBV infections.
  • Dataset covers 169 countries using 2022 WHO-based Hepatitis B estimates and national reporting data.
Hepatitis B Cases by Country Map

Understanding Hepatitis B

Hepatitis B is a viral infection that affects the liver and can cause both acute and chronic disease. The virus spreads primarily through infected blood, birth-related transmission, or other bodily fluid exposure. Chronic HBV infections can persist for decades and remain a major cause of cirrhosis and liver cancer worldwide.

Largest Hepatitis B Burdens Are Concentrated in Asia and Africa

China accounted for the largest estimated chronic HBV burden in the dataset with 79.7 million cases, followed by India at 29.8 million and Indonesia at 17.5 million. Nigeria ranked as the largest African burden with 14.4 million estimated cases, while Ethiopia, Vietnam, and the Philippines also reported several million chronic infections each.

The overall distribution shows a strong concentration across Asia and sub-Saharan Africa, where long-term endemic transmission remains more common. Large population size plays a major role in total case counts, although prevalence rates can differ substantially between countries.

Hepatitis B Cases by Country

#
Country
Cases
Year
1
China
China
79,700,000 2022(WHO)
2
India
India
29,800,000 2022(WHO)
3
Indonesia
Indonesia
17,544,081 2022
4
Nigeria
Nigeria
14,384,770 2022
5
Ethiopia
Ethiopia
7,660,095 2022
6
Vietnam
Vietnam
6,520,442 2022
7
Philippines
Philippines
5,660,072 2022
8
Pakistan
Pakistan
3,796,372 2022
9
Ghana
Ghana
2,865,177 2022
10
DR Congo
DR Congo
2,785,244 2022
11
South Africa
South Africa
2,741,289 2022
12
Angola
Angola
2,715,233 2022
13
Niger
Niger
2,640,230 2022
14
Kenya
Kenya
2,360,984 2022
15
Ivory Coast
Ivory Coast
2,155,631 2022
16
Mozambique
Mozambique
2,034,837 2022
17
Sudan
Sudan
2,019,584 2022
18
Türkiye
Türkiye
1,983,857 2022
19
Tanzania
Tanzania
1,855,605 2022
20
Thailand
Thailand
1,837,909 2022
21
Chad
Chad
1,687,587 2022
22
Russia
Russia
1,650,951 2022
23
Cameroon
Cameroon
1,617,773 2022
24
Mali
Mali
1,581,973 2022
25
South Korea
South Korea
1,395,575 2022
26
Guinea
Guinea
1,379,599 2022
27
Benin
Benin
1,352,927 2022
28
Iran
Iran
1,321,313 2022
29
Iraq
Iraq
1,310,122 2022
30
Zimbabwe
Zimbabwe
1,260,932 2022
31
United States
United States
1,166,550 2022(WHO)
32
Madagascar
Madagascar
1,131,542 2022
33
Uganda
Uganda
1,123,667 2022
34
Syria
Syria
1,121,632 2022
35
Burkina Faso
Burkina Faso
1,089,924 2022
36
Brazil
Brazil
1,038,564 2022
37
Romania
Romania
962,571 2022
38
Egypt
Egypt
952,159 2022
39
Japan
Japan
949,057 2022
40
Yemen
Yemen
948,579 2022
41
Senegal
Senegal
917,427 2022
42
Somalia
Somalia
909,909 2022
43
Togo
Togo
833,679 2022
44
Afghanistan
Afghanistan
748,800 2022
45
South Sudan
South Sudan
744,050 2022
46
Uzbekistan
Uzbekistan
713,947 2022
47
Central African Republic
Central African Republic
644,304 2022
48
Papua New Guinea
Papua New Guinea
593,071 2022
49
Algeria
Algeria
588,849 2022
50
Saudi Arabia
Saudi Arabia
575,956 2022
51
Malawi
Malawi
560,872 2022
52
Tajikistan
Tajikistan
532,731 2022
53
Turkmenistan
Turkmenistan
529,437 2022
54
Sierra Leone
Sierra Leone
525,971 2022
55
Ukraine
Ukraine
505,658 2022
56
Cambodia
Cambodia
496,539 2022
57
Sri Lanka
Sri Lanka
485,573 2022
58
Kazakhstan
Kazakhstan
448,360 2022
59
Tunisia
Tunisia
440,861 2022
60
Mauritania
Mauritania
433,528 2022
61
Malaysia
Malaysia
396,690 2022
62
Belarus
Belarus
374,583 2022
63
Zambia
Zambia
363,042 2022
64
Nepal
Nepal
359,298 2022
65
Venezuela
Venezuela
358,847 2022
66
Kyrgyzstan
Kyrgyzstan
349,644 2022
67
Congo
Congo
329,697 2022
68
Colombia
Colombia
307,755 2022
69
Italy
Italy
303,000 2022
70
Burundi
Burundi
302,315 2022
71
Moldova
Moldova
294,803 2022
72
Laos
Laos
260,495 2022
73
Guinea-Bissau
Guinea-Bissau
259,599 2022
74
Germany
Germany
246,000 2022
75
Lesotho
Lesotho
242,317 2022
76
Liberia
Liberia
228,492 2022
77
Morocco
Morocco
223,645 2022
78
Poland
Poland
220,820 2022
79
Australia
Australia
217,931 2022
80
Haiti
Haiti
217,325 2022
81
Canada
Canada
215,840 2022
82
Rwanda
Rwanda
207,232 2022
83
Greece
Greece
200,000 2022
84
Jordan
Jordan
199,009 2022
85
Mongolia
Mongolia
193,155 2022
86
Albania
Albania
185,474 2022
87
Dominican Republic
Dominican Republic
175,955 2022
88
Eritrea
Eritrea
170,611 2022
89
Gabon
Gabon
169,379 2022
90
Peru
Peru
146,893 2022
91
Botswana
Botswana
146,254 2022
92
Namibia
Namibia
142,736 2022
93
France
France
135,706 2022
94
Israel
Israel
130,671 2022
95
Singapore
Singapore
130,514 2022
96
Timor-Leste
Timor-Leste
122,190 2022
97
Serbia
Serbia
118,750 2022
98
Mexico
Mexico
117,412 2022
99
Oman
Oman
112,358 2022
100
Libya
Libya
111,125 2022
101
Ecuador
Ecuador
108,234 2022
102
Jamaica
Jamaica
107,261 2022
103
Eswatini
Eswatini
104,289 2022
104
Guatemala
Guatemala
103,499 2022
105
New Zealand
New Zealand
86,603 2022
106
United Arab Emirates
United Arab Emirates
84,818 2022
107
Bosnia and Herzegovina
Bosnia and Herzegovina
80,462 2022
108
Argentina
Argentina
78,142 2022
109
Georgia
Georgia
78,000 2022
110
Equatorial Guinea
Equatorial Guinea
77,032 2022
111
Lebanon
Lebanon
71,615 2022
112
Mauritius
Mauritius
67,789 2022
113
Cuba
Cuba
65,742 2022
114
Kuwait
Kuwait
65,455 2022
115
Cape Verde
Cape Verde
62,371 2022
116
Djibouti
Djibouti
61,866 2022
117
Switzerland
Switzerland
61,665 2022
118
Gambia
Gambia
61,609 2022
119
Solomon Islands
Solomon Islands
60,022 2022
120
El Salvador
El Salvador
55,442 2022
121
Nicaragua
Nicaragua
51,643 2022
122
Netherlands
Netherlands
48,756 2022
123
Comoros
Comoros
42,135 2022
124
Portugal
Portugal
41,527 2022
125
North Macedonia
North Macedonia
35,851 2022
126
Paraguay
Paraguay
33,914 2022
127
Qatar
Qatar
30,160 2022
128
Bolivia
Bolivia
29,398 2022
129
Trinidad and Tobago
Trinidad and Tobago
28,920 2022
130
Maldives
Maldives
27,324 2022
131
Honduras
Honduras
26,150 2022
132
Chile
Chile
24,880 2022
133
Vanuatu
Vanuatu
23,998 2022
134
Armenia
Armenia
23,704 2022
135
Ireland
Ireland
22,000 2022
136
Sao Tome and Principe
Sao Tome and Principe
21,073 2022
137
Guyana
Guyana
20,104 2022
138
Norway
Norway
16,375 2022
139
Fiji
Fiji
16,113 2022
140
Denmark
Denmark
14,548 2022
141
Bahrain
Bahrain
13,246 2022
142
Panama
Panama
13,132 2022
143
Bhutan
Bhutan
11,774 2022
144
Suriname
Suriname
11,402 2022
145
Kiribati
Kiribati
10,504 2022
146
Samoa
Samoa
9,646 2022
147
Tonga
Tonga
9,582 2022
148
Montenegro
Montenegro
9,264 2022
149
Costa Rica
Costa Rica
8,520 2022
150
Micronesia
Micronesia
8,328 2022
151
Bahamas
Bahamas
6,437 2022
152
Brunei
Brunei
6,074 2022
153
Seychelles
Seychelles
5,588 2022
154
Uruguay
Uruguay
5,415 2022
155
Belize
Belize
4,711 2022
156
Barbados
Barbados
4,422 2022
157
Saint Lucia
Saint Lucia
2,824 2022
158
Marshall Islands
Marshall Islands
2024 2022
159
Grenada
Grenada
1969 2022
160
Iceland
Iceland
1738 2022
161
Saint Vincent and the Grenadines
Saint Vincent and the Grenadines
1632 2022
162
Antigua and Barbuda
Antigua and Barbuda
1472 2022
163
Dominica
Dominica
1142 2022
164
Palau
Palau
1040 2022
165
Cook Islands
Cook Islands
980 2022
166
Tuvalu
Tuvalu
887 2022
167
Saint Kitts and Nevis
Saint Kitts and Nevis
748 2022
168
Nauru
Nauru
730 2022
169
Andorra
Andorra
376 2022
170
Monaco
Monaco
172 2022
171
San Marino
San Marino
158 2022
172
Niue
Niue
111 2022

Vaccination and Prevention Programs

The Hepatitis B vaccine has been widely used since the 1980s and remains one of the most effective prevention tools against chronic HBV infection. Many higher-income countries significantly reduced transmission through universal childhood vaccination, blood screening programs, and improved infection control practices.

However, vaccination coverage and access to screening still vary widely across regions. In several lower-income countries, limited healthcare access and underdiagnosis continue to contribute to persistent long-term HBV burdens.

About the Data

The figures shown here represent estimated people living with chronic Hepatitis B infection in 2022 based primarily on WHO reporting, modeled prevalence estimates, and national health data. The dataset reflects chronic HBV burden rather than annual new infections or mortality figures.

Frequently Asked Questions

Q: Which countries have the highest Hepatitis B infection rates?

A: Based on 2022 data, Nigeria leads with over 14.3 million cases, followed by Indonesia, 17,544,081 (17.5 million), Pakistan (3.7 million), and Vietnam (6.5 million). The Western Pacific and African regions account for approximately 68% of all chronic Hepatitis B infections globally. These high numbers are primarily due to large populations, historical endemic transmission, and varying levels of vaccination coverage.

Q: How effective is the Hepatitis B vaccine in preventing infection?

A: The Hepatitis B vaccine is highly effective, providing 95% protection against infection when the complete vaccine series is administered. The vaccine has been available since 1982 and is considered one of the safest and most effective vaccines available. Countries with universal infant vaccination programs have seen dramatic reductions in Hepatitis B prevalence, with some achieving near-elimination status. The WHO recommends vaccination for all infants within 24 hours of birth, followed by 2-3 additional doses to ensure complete protection.

Data Disclaimer: Projected data (future years) are estimates based on mathematical models. Actual values may differ. Learn about our methodology →

Sources

  • Updated: 07.11.2025
    https://www.who.int/data/gho/data/indicators/indicator-details/GHO/hepatitis---number-of-persons-living-with-chronic-hepatitis

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